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Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.

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    Final results from the RESPECT trial found that percutaneously closing a patent foramen ovale (PFO) using the Amplatzer PFO Occluder was superior to medical management in the prevention of recurrent ischemic stroke in patients who previously had a cryptogenic stroke.

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    (HealthDay)—A data-driven algorithm for personalized diabetes care can yield substantial improvements in hemoglobin A1c (HbA1c), according to a study published online Dec. 5 in Diabetes Care.

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    (HealthDay)—Left ventricular assist devices (LVADs) improve quality of life in ambulatory patients with advanced heart failure, but increase lifetime costs, according to a study published online Jan. 11 in JACC: Heart Failure.

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    One of the first studies of provider-patient communication regarding weight-management and associated electronic medical records (EMR) finds that many benchmarks of quality weight-management care are not met during primary-care visits with overweight Latino children.

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    Individuals were more likely to undergo surgery to treat narrowed arteries when they were treated by fee-for-service physicians in the private sector compared with salary-based military physicians, according to a study published online by JAMA Surgery.

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    (HealthDay)—For individuals with prediabetes, participation in lifestyle modifications such as the National Diabetes Prevention Program (DPP) is associated with economic benefit, according to a study published online Feb. 13 in Population Health Management.

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    Implementation of a virtual glucose management service (vGMS) was associated with significant improvements in glycemic control among hospitalized patients. The system utilized electronic medical records (EMRs) to review patient insulin/glucose charts and dispatch recommendations for managing patients with hyper- or hypoglycemia. The findings of an observational study are published in Annals of Internal Medicine.

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    Patients undergoing spinal fusion surgery who are treated with methadone during the procedure require significantly less intravenous and oral opioids to manage postoperative pain, reports a new study published in the May issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

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    Across the country, health care is going through a transformation both in how care is delivered and how it is paid for. These alternative payment models, such as Medicare's Accountable Care Organization (ACO), require health care delivery organizations to share in the financial risk associated with their patients' medical spending and encourage health care providers to think of alternative ways to get patients the care that they need. Although ACOs appear to lower medical spending, there is little information on how these savings are actually achieved. Today, researchers at Partners HealthCare published a study showing that Partners Pioneer ACO not only reduces spending growth, but does this by reducing avoidable hospitalizations for patients with elevated but modifiable risks. The study appears in the May issue of the journal Health Affairs.

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    In one of the first studies of its kind, nearly one-third of 10,000 older adults were prescribed opiate pain medications such as morphine, Percocet and OxyContin while hospitalized for non-surgical conditions, a course of care significantly linked to poor outcomes such as being restrained and requiring bladder catheterization, according to startling new research by Northwell Health physicians.

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    A study funded by Marie Curie and Dimbleby Cancer Care published today shows the potential benefits of a new nurse-led intervention in supporting carers to manage pain medication in people with terminal cancer.

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    Proteins must be in the right place at the right time in the cell to function correctly. This is even more critical in a neuron than in other cells because of its complex tree-like structure and its function. Researchers at Thomas Jefferson University have now discovered how phosphorylation, a common type of protein modification, functions in a novel way to change the location of proteins that are critical for both neuronal function and pathological pain. They find that phosphorylation can occur outside of the neuron and impacts protein function, localization and the sensation of pain.

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    More than 130,000 Anterior Cruciate Ligament (ACL) surgeries take place each year with the majority of patients not requiring pain medication after three months post-operatively. However, researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Annual Meeting today in Toronto, Ontario, Canada found that those patients who were filling opioid prescriptions prior to surgery were 10 times more likely to be filling prescriptions five months after surgery.

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